Before using the spray, the bottle should be primed by pressing the piston once or twice. In sinus procedures 3 sprays are used.In dentistry, the normal dose is 1-5 sprays. Two sprays per quarter of the mouth is recommended, with a maximum of 3 sprays per quarter of the mouth over 30 minutes Up to 20 sprays may be necessary in childbirth and procedures of the throat and windpipe. Lower doses are used for children aged 3-12 years.